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SLAC researchers develop an approach to better guide the preparation of cell slices for cryogenic electron tomography imaging. It’s tricky business taking images of tiny structures within cells. One technique, cryo-electron tomography (cryo-ET), shoots electrons through a frozen sample. The images formed by the electrons that emerge allow researchers to reconstruct the internal architecture of a cell in 3D with near-atomic resolution. The thing is, this method doesn’t work if a sample is too thick. Electrons can’t penetrate through most cells, including human cells. Instead, researchers use a beam of ions to mill these beefier cells down to 200 nanometer-thick…
The mobile-first design methodology is great—it focuses on what really matters to the user, it’s well-practiced, and it’s been a common design pattern for years. So developing your CSS mobile-first should also be great, too…right? Article Continues Below Well, not necessarily. Classic mobile-first CSS development is based on the principle of overwriting style declarations: you begin your CSS with default style declarations, and overwrite and/or add new styles as you add breakpoints with min-width media queries for larger viewports (for a good overview see “What is Mobile First CSS and Why Does It Rock?”). But all those exceptions create complexity…
Surveillance technology is advancing faster than the laws meant to govern it. Across the United States, police departments are deploying automated license plate readers, facial recognition tools, and predictive systems that quietly log the daily movements of millions of people. These tools promise efficiency and safety, but critics argue that they represent a form of warrantless mass surveillance, and raise deep constitutional questions about privacy, accountability, and the limits of government power in the digital age. Michael Soyfer is an attorney at the Institute for Justice, a nonprofit public interest law firm focused on defending individual rights. His work centers…
It can be tricky to figure out how to clean your Keurig, but it’s important work. If your household is like mine, your pod coffee maker runs anywhere from three to seven times per day. All of that use can cause buildup and gunk, which can affect the taste of your coffee and the lifespan of your machine. But with proper maintenance and a dedicated routine, cleaning is a breeze. Here’s everything you need to know about light daily cleaning as well as deeper cleans.Be sure to check out our related buying guides, including the Best Pod Coffee Makers, the…
Long before Taco Tuesday became part of the pop-culture vernacular, Tuesdays were synonymous with security — and for anyone in the tech world, they still are. Patch Tuesday, as you most likely know, refers to the day each month when Microsoft releases security updates and patches for its software products — everything from Windows to Office to SQL Server, developer tools to browsers. The practice, which happens on the second Tuesday of the month, was initiated to streamline the patch distribution process and make it easier for users and IT system administrators to manage updates. Like tacos, Patch Tuesday is…
IBM on Thursday announced IBM Sovereign Core, a new software offering designed to help enterprises, governments, and service providers build, deploy, and manage AI-ready environments under full sovereign control. The company said the product is the industry’s first “AI-ready sovereign-enabled” software, addressing regulatory, governance, and geopolitical pressures around data and artificial intelligence.Addressing the Growing Demand for Digital SovereigntyAs organizations deploy AI workloads, concerns around digital sovereignty have intensified. Beyond data residency, sovereignty encompasses who operates and controls technology infrastructure, how data and identities are governed, where workloads run, and under whose jurisdiction AI models operate. IBM said in an official…
The shift toward data-driven decision-making is reshaping how businesses operate, compete, and grow. Machine learning plays a central role in this transformation by enabling organizations to uncover patterns, predict outcomes, and automate insights at scale. For leaders aiming to move from intent to measurable impact, this article presents a practical roadmap for implementing machine learning in business applications that prioritizes business outcomes, operational feasibility, and long-term value creation. Summarize this article with ChatGPT Get key takeaways & ask questions What is Machine Learning in a Business Context? Machine learning (ML) refers to the use of algorithms that enable systems to…
It is 2026, and in the era of Large Language Models (LLMs) surrounding our workflow, prompt engineering is something you must master. Prompt engineering represents the art and science of crafting effective instructions for LLMs to generate desired outputs with precision and reliability. Unlike traditional programming, where you specify exact procedures, prompt engineering leverages the emergent reasoning capabilities of models to solve complex problems through well-structured natural language instructions. This guide equips you with prompting techniques, practical implementations, and security considerations necessary to extract maximum value from generative AI systems. What is Prompt Engineering Prompt engineering is the process of…
Astro Technology Company, maker of the Astro web framework, has just been acquired by Cloudflare. The company also just released Astro 6 in beta, with the update featuring a redesigned development server. The merger with Cloudflare means Astro remains open source and MIT-licensed and continues to be actively maintained, according to the January 16 announcement. In addition, Astro will continue to support a wide set of deployment targets, not only Cloudflare, and Astro’s open governance and development roadmap remain in place. Full-time employees of The Astro Technology Company are now employees of Cloudflare, said the announcement. A separate blog post…
One thing I hear consistently from business leaders is this: We believe in the promise of AI, but we’re still figuring out how to turn it into real business growth. At Cisco, this is the journey we’re on. Over the past 18 months, we’ve invested in AI tools and learning experiences designed to help people enhance their work and deliver measurable business results. To understand whether those investments are making a difference, the People & Communities team stepped back and asked a bigger question: When AI becomes integral to how our people work, how does it shape engagement, performance, and…
