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Moon, C. Y. et al. Dendritic cell maturation in cancer. Nat. Rev. Cancer 25, 225–248 (2025).Article  CAS  PubMed  PubMed Central  Google Scholar  You, Q. et al. A nanovaccine targeting cancer stem cells and bulk cancer cells for postoperative cancer immunotherapy. Nat. Nanotechnol. 20, 1298–1311 (2025).Zhou, J. et al. STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity. Nature 643, 519–528 (2025).Shapir Itai, Y. et al. Bispecific dendritic-T cell engager potentiates anti-tumor immunity. Cell 187, 375–389.e318 (2024).Article  CAS  PubMed  Google Scholar  Eweje, F. et al. Self-assembling protein nanoparticles for cytosolic delivery of nucleic acids and proteins. Nat. Biotechnol. (2025).Meiser,…

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I attended the first Pragmatic Summit early this year, and while there host Gergely Orosz interviewed Kent Beck and myself on stage. The video runs for about half-an-hour. I always enjoy nattering with Kent like this, and Gergely pushed into some worthwhile topics. Given the timing, AI dominated the conversation – we compared it to earlier technology shifts, the experience of agile methods, the role of TDD, the danger of unhealthy performance metrics, and how to thrive in an AI-native industry.  ❄                ❄                ❄                ❄                ❄ Perl is a language I used a little, but never loved. However the definitive book on it, by…

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Everest Group has released findings from its latest study, Key Priorities for Technology and Services Spend in 2026, revealing how organizations must fundamentally rethink technology and services investments to navigate a “permacrisis” environment, an era defined by sustained geopolitical, economic, and regulatory disruption.  Drawing on insights from a global survey of more than 200 senior decision-makers from large organizations, including CIOs, CTOs, procurement executives, and business unit leaders, alongside executive interviews and Everest Group’s ongoing market intelligence, the study reflects perspectives from organizations across North America, Europe, and Asia-Pacific.   All respondents represent organizations with annual revenues exceeding US$1 billion and hold direct responsibility for, or influence over, spend and investment decisions for technology…

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This story appeared in Today, Explained, a daily newsletter that helps you understand the most compelling news and stories of the day. Subscribe here.Live Nation will have to face the antitrust music, a federal jury in New York ruled this week, declaring that America’s preeminent concert middleman is an illegal monopoly. This was not news to those of us who’ve attended a concert in the past, oh, dozen years. You could score a ticket to Celine Dion’s comeback tour with all the money I’ve tithed to Live Nation in service fees and charges.The verdict is an important recognition, however, that…

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The real danger isn’t that machines will act without oversight; it’s that human overseers have no idea what the machines are actually “thinking.” Thankfully, science may offer a way forward. Read the full op-ed on the urgent need for new safeguards around AI warfare. The must-reads I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology. 1 Despite blacklisting Anthropic, the White House wants its new modelTrump officials are negotiating access to Mythos. (Axios)+ Anthropic said it was too dangerous for a public release. (Bloomberg $)+ Finance ministers are alarmed about the security risks. (BBC)+ Anthropic just…

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Every business needs a professional email address, but not every business has the budget for one right away. I’ve tested and reviewed dozens of email hosting providers and business tools, and in this guide, I break down the best legitimate ways to get a free business email address in 2026. Some are completely free, while others bundle email with domains, hosting, or productivity software. All options listed here are secure, credible, and suitable for real business use and not risky “free email hacks.” Business email providersBest forStarting paid price Zoho MailFree business email accounts$1 per user (billed annually) Proton MailSecurity…

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Microsoft today pushed software updates to fix a staggering 167 security vulnerabilities in its Windows operating systems and related software, including a SharePoint Server zero-day and a publicly disclosed weakness in Windows Defender dubbed “BlueHammer.” Separately, Google Chrome fixed its fourth zero-day of 2026, and an emergency update for Adobe Reader nixes an actively exploited flaw that can lead to remote code execution. Redmond warns that attackers are already targeting CVE-2026-32201, a vulnerability in Microsoft SharePoint Server that allows attackers to spoof trusted content or interfaces over a network. Mike Walters, president and co-founder of Action1, said CVE-2026-32201 can be…

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Support CleanTechnica’s work through a Substack subscription or on Stripe. Sometimes story pitches are sent to my personal email address, and some are not at all appropriate. Recently, someone sent some nonsensical information about how the transition to electric vehicles from gas and diesel vehicles will take 100 years or more because installing public EV chargers takes too long. Such a view is both false and overly pessimistic.  For example, it was just announced that 2,926 new public EV chargers will be installed in Belgium in the next two years. Two years, not 20, not 200 — 2 years. That…

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What we like about it: The Dream Duo 2 includes the Owlet Smart HD monitor and the Owlet Dream Sock. The Owlet is the only FDA-cleared infant health monitor on this list. The Dream Sock is the first and only over-the-counter medical pulse oximetry solution for infants. The package came with four different-sized socks that are meant to fit healthy infants weighing 6 pounds to 30 pounds. The socks contain a photoplethysmography (PPG) sensor, similar to what hospitals use to measure your heart rate. The sock has velcro straps so you can easily adjust it around your child’s foot. One thing…

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The President’s 2026 Budget requests $1.45 billion for the NNI, with key investments in foundational research that will fuel new discoveries and in application-driven R&D to advance technologies of the future and address national priorities. Cumulative NNI funding since its inception in 2001 totals nearly $47 billion (including the 2026 request). The President’s 2026 Budget supports nanoscale science, engineering, and technology R&D at 10 agencies. See the graph at right for funding trends since the inception of the NNI. The NNI Supplement to the President’s 2026 Budget documents progress of the NNI participating agencies in addressing the goals and objectives…

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