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A black phosphorus-based system detects micro-RNA in aqueous humor, enabling safe diagnosis of Primary Central Nervous System Lymphoma RNA chain (Courtesy: iStock/Christoph Burgstedt) Early diagnosis of primary central nervous system lymphoma (PCNSL) remains challenging because brain biopsies are invasive and imaging often lacks molecular specificity. A team led by researchers at Shenzhen University has now developed a minimally invasive fibre-optic plasmonic sensor capable of detecting PCNSL-associated microRNAs in the eye’s aqueous humor with attomolar sensitivity. At the heart of the approach is a black phosphorus (BP)–engineered surface plasmon resonance (SPR) interface. An ultrathin BP layer is deposited on a gold-coated…
I offer a single bit of advice to friends and family when they become new parents: When you start to think that you’ve got everything figured out, everything will change. Just as you start to get the hang of feedings, diapers, and regular naps, it’s time for solid food, potty training, and overnight sleeping. When you figure those out, it’s time for preschool and rare naps. The cycle goes on and on. Article Continues Below The same applies for those of us working in design and development these days. Having worked on the web for almost three decades at this…
To anyone who doesn’t dream of labor, the idea of a personality hire — a person who gets jobs because they’re a fun, unique human to be around — can be a bit jarring. And there’s an idea that might be even more puzzling than the existence of personality hires: that these people can teach us valuable lessons about being hired today. It would behoove us to start thinking about the job process through the eyes of a charming, pleasant, fun, distinctly human personality hire.Statistically, today’s job market is not great. But more than that, the inevitable creep of AI…
In practical terms, that means not one-size-fits-all chatbots like ChatGPT and Gemini, but instead a series of AI-based technologies, each pointed at solving an important problem and aimed at bettering people’s lives. The first two to be rolled out will be for medicine and improving energy efficiency. The Google enterprise threat All that being said, Gemini’s emergence as the world’s premier chatbot does present potentially serious problems for Microsoft. Microsoft 365 Copilot, which requires an add-on subscription, hasn’t been adopted in enterprises the way the company had hoped. A year ago, Microsoft announced that almost 70% of Fortune 500 companies…
What will everyone be talking about at PTC’26, and what headlines do you need to brush up on to make the most of the event? This is what our team has been thinking about as we prep for the January conference and outline our annual telecom workshop. (No spoilers on that just yet, but watch this space.) The good news is that you can borrow from our expert conference planning.
For decades, Windows has been the platform for PC gaming: open, flexible and built with players in mind. From the days of classics like Diablo to today’s cutting-edge experiences powered by DirectX and AI-driven graphics, Windows has partnered with developers, creators, OEMs and silicon innovators to push hardware and software forward. That collaboration continues to deliver new ways to play, whether on powerful desktops or purpose-built handheld devices. In 2025, Windows 11 gaming became faster, more portable and more visually immersive. We introduced a purpose-built handheld experience with the ROG Xbox Ally and ROG Xbox Ally X, expanded gaming capabilities for Windows-powered Arm laptops and shipped DirectX advances that boosted ray tracing performance by up to 2.3× on supported hardware, paving the way for neural rendering. Together with the gaming community, our commitment is to make…
The race for the “best AI model” goes on, as Z.ai is the latest one to mark its entry with a new and evolved model. Calling it the GLM-4.6V, Z.ai has focused on visual cues and representation with this one. And hence the “V” at the end of its name that resembles the existing flagship model by the company the GLM-4.6 (read all about it here). So, of course, this one is not just another chat model. It sees images, understands charts, writes code, and even reasons like a real teammate who actually pays attention. And the fun part –…
The most profound technologies are those that disappear. They weave themselves into the fabric of everyday life until they are indistinguishable from it.– Mark WeiserMany of us grew up watching Star Trek, where the crew could simply speak to the computer and it would understand not just their words, but their intent. “Computer, locate Mr. Spock” wasn’t just about voice recognition – it was about comprehension, context, and action. This vision of ambient computing, where the interface disappears and interaction becomes natural (speech, gestures, and so on), has been a north star for scientists and builders for decades.The computing research…
It’s an increasingly common surprise: a package shows up at your door with your name and your address…but you never ordered it. These unsolicited deliveries may seem harmless, but they’re often tied to a scheme called a brushing scam. These scams occur year-round but tend to pick up around the holidays or peak shopping seasons, when shipping volume spikes and it’s easier for suspicious packages to blend in. Below is everything you need to know: how brushing scams work, what they mean for your personal information, and the exact steps to take if one shows up at your doorstep. What You Need to Know A brushing scam is when a seller sends you…
Hiking boot maker Keen has snagged a former NASA climate scientist to head up sustainability, philanthropy and advocacy. Ann Radil is the new senior director of the Keen Effect, the company’s impact program, where she is leading climate action, circular economy programs and attempts to ramp up green chemistry. The Portland, Oregon-based footwear company was an early mover in phasing out “forever chemicals” such as poly- and per-fluoroalkyls (PFAS), used in water- and stain-resistance. Radil quietly started on Sept. 27 as the brand debuted during Paris Fashion Week. She reports to CEO and President Rory Fuerst. “Though I’m just getting started,…