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To date, the scientific progress of drug discovery has largely evolved through three paradigms: serendipitous or empirical drug discovery (SDD) (from ancient times to the 19th century), phenotypic drug discovery (PDD) (mid-19th century to the 1950–1960s), and target-based drug discovery (TDD) (from the molecular biology revolution of the 1980s to the present) [1], [2]. Despite increasing investments in drug research and development over the years, the field continues to face the “Eroom’s law” phenomenon-where research and development (R&D) costs double approximately every nine years, while the number of new drugs produced per billion dollars of investment halves over the same…
Anthropic releases Claude Sonnet 4.6 Claude Sonnet 4.6 features improved skills in coding, computer use, long-context reasoning, agent planning, knowledge work, and design. It is now the default model in claude.ai and Claude Cowork, has a 1M context window (beta), and is priced the same as Sonnet 4.5, at $3 per million input tokens and $15 per million output tokens. “Performance that would have previously required reaching for an Opus-class model—including on real-world, economically valuable office tasks—is now available with Sonnet 4.6. The model also shows a major improvement in computer use skills compared to prior Sonnet models,” Anthropic wrote…
China’s Great Firewall is often spoken about but is rarely understood. It is one of the most sophisticated and opaque censorship systems on the planet, and it shapes how over a billion people interact with the global internet, influences the design of privacy and proxy tools worldwide, and continues to evolve in ways that challenge researchers, developers, and policymakers alike. Jackson Sippe is a PhD researcher at the University of Colorado Boulder whose work focuses on uncovering how national-scale censorship systems operate. Jackson recently helped lead a groundbreaking study analyzing a previously undocumented GFW technique that quietly broke fully encrypted…
KBIS 2026 was full of industry firsts. Much of the innovation on display at the sprawling home and kitchen showcase involved large appliances. Top brands, including Samsung, LG, GE and Sharp, were on hand to give a glimpse into the future of home tech.We were there to see it all up close and speak with product managers, engineers and brand reps about all the new large-appliance features coming in 2026. The latest fridges, ovens, dishwashers and laundry systems were well represented on the show floor, and the innovations on display weren’t just flashy — they were practical upgrades designed to make home…
UiPath’s acquisition of WorkFusion reflects the ongoing shift in automation from horizontal enablement to vertically specialized, agentic solutions. WorkFusion brings pre-built Artificial Intelligence (AI) agents designed for Financial Crime Compliance (FCC), strengthening UiPath’s presence in Banking and Financial services (BFS). Beyond portfolio expansion, the transaction signals a broader market transition toward embedding domain-specific AI agents and regulatory intelligence directly within verticalized agentic automation offerings. Reach out to discuss this topic in depth. What happened UiPath acquired WorkFusion to strengthen its agentic automation portfolio in BFS, with a particular focus on FCC. WorkFusion brings pre-configured AI agents designed to automate high-volume compliance workflows, including customer onboarding and screening, alert triage, case investigation, and Transaction Monitoring (TM) across Anti-money Laundering (AML) and Know Your Customer (KYC) processes. Beyond incremental capability expansion, the transaction…
Fiber ISPs are very much on the rise in South Africa, with multiple players gaining traction with their regional rollouts. Unusually, the majority of these operators use an open access business model, allowing dozens of smaller companies to market and resell fiber connectivity. In 2025 a regulatory U-turn paved the way for Vodacom South Africa to acquire a co-controlling stake in MAZIV – a deal that had first been tabled four years earlier. Going forward, Vodacom expects to combine its domestic fibre assets with MAZIV affiliates Vumatel and Dark Fibre Africa (DFA) to create an enlarged fiber provider. With Vumatel’s…
Satya Nadella, Chairman and CEO, and members of his executive team shared the following communications with employees today. SATYA NADELLA MESSAGE Gaming has been part of Microsoft from the start. Flight Simulator shipped before Windows, and you can practically ray‑trace a line from DirectX in the ’90s to the accelerated‑compute era we’re in today. As we celebrate Xbox’s 25th year, the opportunity and innovation agenda in front of us is expansive. Today we reach over 500 million monthly active users, are a top publisher across all platforms, and continue to innovate across gaming hardware, content, and community, in service of…
Mainframe programmers are problem-solvers. In today’s large, complex data centers, we’re often faced with ad-hoc questions from management – questions that echo the old National Enquirer slogan, “Inquiring Minds Want to Know.” And management usually wants answers right now: What does this dataset look like? What are its characteristics? How much space does it occupy? When was it created and last referenced? For a single dataset, this sort of information can usually be obtained with a glance at an ISPF panel or two. For a list of datasets, though, it’s not so simple. We need to obtain detailed data for…
Last week, we took a major step forward with the availability of Claude Opus 4.6 in Microsoft Foundry, bringing frontier AI capable of deep reasoning, agentic workflows, and complex decision-making to enterprise developers and builders. If Opus represents the highest tier of AI performance, Sonnet 4.6 builds on that momentum by delivering nearly Opus-level intelligence at a lower price, while often being more token efficient than Claude Sonnet 4.5. Claude Sonnet 4.6 is available today in Microsoft Foundry, and it is designed for teams who want frontier performance across coding, agents, and professional work at scale. With Sonnet 4.6, customers…
Ravie LakshmananFeb 21, 2026Artificial Intelligence / DevSecOps Artificial intelligence (AI) company Anthropic has begun to roll out a new security feature for Claude Code that can scan a user’s software codebase for vulnerabilities and suggest patches. The capability, called Claude Code Security, is currently available in a limited research preview to Enterprise and Team customers. “It scans codebases for security vulnerabilities and suggests targeted software patches for human review, allowing teams to find and fix security issues that traditional methods often miss,” the company said in a Friday announcement. Anthropic said the feature aims to leverage AI as a tool…